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Abbreviations: SIRT1: Sirtuin1

SGLT-2 inhibitor and GLP-1 receptor agonist treatment for patients with nonalcoholic fatty liver disease and type 2 diabetes mellitus: is their combination the optimal treatment option

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This review was supported by intramural GRASP award 2190268 from LLU

Meanwhile, cryo-EM structures of ABCC1, CFTR, and Ycf1 reveal a mostly disordered R-domain 22,23,24 without assigned sequence for the phosphorylation sites, limiting our understanding of R-domain interactions