The FDA warns that both CJC-1295 and ipamorelin are risky for immunogenicity, potentially causing life-threatening outcomes such as anaphylaxis.25 26 Cardiovascular concerns: Specifically concerning CJC-1295, the FDA warns of the risk of increased heart rate and systemic vasodilatory reaction, including flushing, warmth, and transient hypotension.25 27 Cancer: With their ability to increase the rate of cellular replication, growth hormone secretagogues in general are unsafe for cancer survivors and people with an active cancer diagnosis.28 Secretagogue use may elevate their risk for recurrence or worsen their prognosis
Di Bisceglie AM, Axiotis CA, Hoofnagle JH, Bacon BR
Here is what before and after results look like by timeline, by sex, and what the trial data actually shows
However, healthy individuals synthesise glutathione endogenously at rates sufficient to meet this demand if dietary intake of cysteine, glutamate, and glycine is adequate
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