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Pratley said the best course of action for treating CKD may be to prescribe both an SGLT2 inhibitor and semaglutide so the drugs work synergistically to offer the greatest benefits

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The subtopics parse the primary mechanisms and real-world implications, spanning what occurs, why it is significant, where it manifests, and how to detect or mitigate risk

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This is clinical education, not medical advice, and nothing here should be read as a treatment recommendation, protocol, or dosing guidance