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Renal and hepatic function can influence elimination rates, though semaglutide's elimination is less dependent on these organs compared to many other medications
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Thyroid dysfunction : An underactive thyroid slows metabolism significantly, making fat burning difficult even with appetite suppression in place
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Biochemical assays As previously described [11], the levels of malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and the ratio of glutathione (GSH)/glutathione disulfide (GSSG) were assessed using the MDA detection kit, total SOD assay kit with WST-8, total GSH-Px assay kit, and GSH and GSSG assay kit (Beyotime), respectively
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