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SPF mice were intraperitoneally injected with the GLP-1 receptor (GLP-1R) agonist exenatide (Ex-4), and ABX mice were intraperitoneally injected with the GLP-1R antagonist exendin 9-39 (Ex(9-39)) (Fig

At the start of the study they weighed about 255 pounds, on average

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While GLP-1 RAs are commonly associated with acute pancreatitis, emerging reports suggest a possible association with pancreatic cystic lesions, even in patients without typical risks factors such as alcohol, gallstones, or hereditary syndromes