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In consequence, acylcarnitines constitute an appreciable component of the tissue carnitine pool, and tissue and plasma concentrations of carnitine and acylcarnitines are together maintained within relatively narrow limits by a variety of mechanisms, which influence in turn innumerable aspects of carbohydrate and lipid metabolism, including the regulation of insulin secretion by pancreatic -cells and the determination of tissue insulin sensitivity

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Thus, repurposing of drugs that are Food and Drug Administration (FDA)-approved may have the potential of being used as an adjuvant treatment

Journal of clinical gastroenterology, 53 (10), e416-e423

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