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Senescence is a major contributor to aging and the development of cardiovascular disease (123), and sirtuin-1 expression is required for metformin to protect endothelial cells against hyperglycemia-induced senescence (110)

Ozempic is an injectable drug thats approved by the Food and Drug Administration (FDA) to help treat people with type 2 diabetes when other medications havent been able to effectively manage their blood sugar

Some have speculated that because Mounjaro targets both PIP and GLP-1 receptors, that may lead to patients losing more weight, though this has not been proven

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+ GLP-1 agonists, a class of medications, mimic the effects of GLP-1 in the body