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Because GLP-2 acts through subepithelial myofibroblasts, which are the same cell population implicated in intestinal fibrogenesis, the risk-benefit profile of GLP-2 agonism may differ substantially between mucosal UC, inflammatory ileal CD, and stricturing or penetrating CD phenotypes, and this phenotypic stratification should be a required feature of future trial design
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Naltrexone/bupropion ER is contraindicated in patients with seizure disorders
The UAE Ministry of Health granted the marketing authorization for Lilly's Trulicity (dulaglutide) solution for injection
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