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The MR analyses indicated that the MR effect estimates of GST ( = 0.0352, P = 0.0047, FDR = 0.0164) and TPO ( = 0.0531, P = 0.0003, FDR = 0.0021) were significantly associated with cognitive performance elevation

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The selective mechanism is particularly valuable because it avoids the collateral damage to healthy cells that occurs with cytotoxic chemotherapy approaches to senescent cell elimination

J Med Chem 66:36563663 Zhang X, Belousoff MJ, Liang Y-L, Danev R, Sexton PM et al (2021) Structure and dynamics of semaglutide and taspoglutide bound GLP-1R-Gs complexes