retatrutide legal in us Side Effects: What Patients Should Know Retatrutide, an investigational triple hormone

Obesity significantly increases loading forces on the knees, hips, ankles, and spine, accelerating cartilage degradation and contributing to osteoarthritis development and progression

The results demonstrated a dose-dependent effect on weight loss, with the maximum reduction reaching 14.7%, compared to only 2.3% in the placebo group

By indication, the obesity and weight management segment held a 28% share of the market in 2025 and is expected to grow at the fastest CAGR of 18.6% during the projection period

Because they slow digestion, GLP-1 drugs may interact with some medications and make them not work as well

According to NICE guidance (NG28) , GLP-1 agonists are recommended for type 2 diabetes when metformin and other treatments have not achieved adequate control