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Common side effects during the adjustment period (typically the first 24 weeks): Mild nausea usually less intense than when first starting a GLP-1 medication Changes in appetite (some patients notice less appetite suppression early on at the starting 0.25 mg dose) Mild stomach discomfort, bloating, or constipation Injection site reactions Side effects that are less likely during the switch (compared to first-time GLP-1 use), but still possible: Significant vomiting less common given prior GLP-1 exposure, but possible Hypoglycemia particularly relevant for type 2 diabetes patients on insulin or sulfonylureas

This can be dangerous

The PSE has a primary role in the generation of colonic slow waves, affecting motility

Drug interactions might not be the first thing that comes to mind when you walk up to the supplements shelf in a store after all, its called drug interactions but its actually something worth considering

Here are some key considerations: Thyroid Disorders: Hypothyroidism can slow down metabolism, making weight loss more difficult