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The relevant question is not "did GLP-1 increase by a percentage" but "did GLP-1 increase to a level that produces clinically meaningful effects on appetite and weight?" Consider this comparison

Lancet 381 , 117124 (2013)

To investigate the possible mechanism of PanIN progression in humans, Gier et al

Taking a few calm, methodical steps before and during each shot keeps the process quick and nearly painlessand it sharply lowers the risk of injection site reactions like redness or itching

A maintenance dose may be lower than the dose used during active weight loss, but it can also be the same dose or even a relatively high one