This variability restricted the possibility of conducting a meta-analysis and emphasized the need for standardized protocols in future research
According to FDA guidance, GLP-1 medications are not recommended for people who have: Pregnancy, because safety data are limited and pregnancy requires appropriate weight gain and nutrient storage A prior history of pancreatitis, due to a risk of triggering inflammation of the pancreas A history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN2), a rare genetic condition linked to thyroid cancer in animal studies A clinician will review your medical history carefully to determine whether these medications are appropriate for you
Alcohol and other substance use disorders are common, and clinicians should be prepared to recognize them, just like hypertension and diabetes
If thats the case, clinicians recommend not stopping abruptly
While formulations differ in dosing frequency, onset, and tolerability, they show broadly comparable safety and efficacy
