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This normalization of cortisol rhythm has downstream effects on mood, energy, appetite, and cognitive function that extend well beyond the sleep period itself

Curr Alzheimer Res 16(13):12161229

In fact, its been found that B12 supplements taken orally are just as effective as intramuscular shots in overcoming states of deficiency when you take up to 1,000 micrograms a day

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They are water-soluble which just means that if theres anything in excess, it will be just excreted through urine or bile