They found that even without causing weight loss, retatrutide had anti-tumor effects that were similar to the currently used (and incredibly expensive) immunotherapy.[ref] A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Animal studies may show the mechanism
Management of hyperglycaemia in type 2 diabetes, 2022: a consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) Diabetologia
Excess insulin can lead to insulin resistance, which reduces insulin effectiveness and leads to high blood sugar levels
Results suggested that Sermorelin may contribute to a variable increase in growth hormone release, ranging from 70% to 107%, over a 12-hour period from somatotroph cells that produce growth hormone in response to brain signals
The 7% body weight reduction observed in mouse models may not translate proportionally to human weight loss it could be more, less, or require entirely different dosing and duration
