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The combination of phenylbutyrate (PBA) and 1,25-dihydroxyvitamin D3 (1,25(OH) 2 D3) induces LL-37 expression in a lung epithelial cell line and enhances M.tb killing in human monocyte-derived macrophages through activation of autophagy and resolution of lung pathology [150]

4 Future prospects In recent years, the importance of controlling redox homeostasis, particularly through glutathione, has been increasingly recognized as crucial for inducing a resistant response

Cellular GSSG accumulation, as opposed to GSH reduction, rendered hepatocytes susceptible to TNF cytotoxicity Increased GSSG/GSG ratios in response to H 2 O 2 exposure can stem from both GSH reduction and GSSG accumulation (data not shown)

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J Anal Bioanal Chem