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If you are experiencing insomnia on semaglutide or constipation on semaglutide , switching to tirzepatide may or may not improve those specific symptoms, but the thirst issue will likely persist because the underlying GLP-1 mechanism is the same

Hasanein and A

The FDA has not approved this combination

People with heart failure, chronic kidney disease, or on fluid restriction should follow their healthcare provider's specific guidance on fluid intake

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