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Reduced potency means your 5mg dose might not actually deliver 5mg of active medication

They also had greater decreases in monthly alcohol consumption, drinks per drinking day, self-reported alcohol craving, and harmful alcohol use measures

[DOI] [PubMed] [Google Scholar] 51.Meijerink AM, Ramos L, Fleischer K, Veltman JA, Hendriks JC, Braat DD

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Other effects of GLP-1 receptor agonists Although previous studies reported that GLP-1 agonists induced an increase in blood pressure as an acute response, mediated by activation of the sympathetic nervous system [4, 49], it was also notedespecially as a long-range effect in clinical settingthat these drugs could decrease blood pressure, as described in multiple reviews [50,51,52,53]