The drug companies believe that hitting more receptors induces better weight-loss effects, which does appear to be true, but when it comes to what this is doing across different immune populations, downstream signaling can be completely changed by adding on these extra agonists, she says
The winner may be the company that best balances efficacy, tolerability, supply, pricing, payer coverage, and patient persistence
This context matters when evaluating whether GLP-1 medication is "too expensive." A $300 annual cost (insured + savings card) or even a $5,000 annual cost (LillyDirect cash pay) must be weighed against the downstream medical costs it prevents
Isolation of iodide-oxidizing bacteria from iodide-rich natural gas brines and seawaters
The effect of adding L-carnitine to omega-3 fatty acid diets on productive performance, oxidative stability, cholesterol content, and yolk fatty acid profiles in laying hens