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We agree with commenters that it is important for hospitals to have a lookback period of at least 12 months prior to posting the file to provide MRF users with meaningful and comparable data, and that this may require additional flexibility

however, compounded drugs themselves are not FDA-approved for safety or effectiveness

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Other differences include the ingredients used in the formulation and dosing flexibility

The finding that 88% of medications retained potency well beyond expiration dates does not apply to peptide drugs, which are inherently less stable than conventional small molecules