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The subject headings and text keywords included those related to the population of interest (i.e., IC, BPS), intervention (relevant treatments such as medication, instillation, intravesical injection, physical therapy and/or others), comparison (placebo or control), and outcomes of treatments: 1) individual symptoms (pain, frequency, urgency and nocturia), 2) structured questionnaires (interstitial cystitis problem index [ICPI], interstitial cystitis symptom index [ICSI], pelvic pain urgency frequency symptom scale [PUF] and functional bladder volume [FBV])
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10.1038/nm919 41 ElgassK.PakayJ.RyanM
Adeno-associated virus as a delivery vector: from basics to therapeutic applications Adeno-associated virus (AAV) belongs to human Parvovirus with a single-stranded DNA genome and is one of the smallest known viruses (~25 nm)
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