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Accessed November 11, 2020

Pennisi, Metab

Many patients prefer injections because they can be completed quickly during a short office visit and become part of a routine wellness schedule

Notably, addition of hemin or pyruvate, a source for NAD+ did not impact these growth phenotypes, suggesting that amelioration of heme defect or respiration inhibition is not sufficient to overcome anti-proliferative effects of mitochondrial GSH depletion (Extended Data Fig