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The 48 week BELIEVE Phase 2 compared a multiple placebo arm to semaglutide4 (1.0mg or 2.4mg), bimagrumab (10 mg/kg, 30 mg/kg), and sema-bima (1.0mg, 2.4mg semaglutide X 10 mg/kg, 30 mg/kg bimagrumab)

The concentration and purity of RNA were determined using a NanoDrop 2000 spectrophotometer from Thermo Fisher Scientific (Waltham, MA, USA)

The safety data over 48 weeks was equally reassuring for those considering long-term treatment

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some studies suggest an association, others do not