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Osteoarthritis primarily affects weight-bearing joints and causes deformity, limitation of motion, and progressive disability

In addition, in PC12 and N2a cells, low-concentration administration of berberine significantly reduced the amount of ROS generation, lipid peroxidation, and DNA fragmentation, and at the same time increased glutathione content and superoxide dismutase activity (Sadeghnia et al., 2017)

Effects of polychlorinated biphenyl (Aroclor 1254) on steroidogenesis and antioxidant system in cultured adult rat Leydig cells

Izadi M, Rezvani M E, Aliabadi A, et al

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