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Particularly, liraglutide attenuates pre-established atherosclerosis throughout the aorta and aortic root in ApoE -/- mice via increasing macrophage polarization into anti-inflammatory macrophages and by reducing the number of pro-inflammatory macrophages [92]

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To date, liraglutide, semaglutide, albiglutide, and dulaglutide (but not exenatide or lixisenatide) have shown superiority compared to placebo for reduction in a 3P-MACE endpoint (62)