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It is important that we do not unintentionally cause harm while looking to appease our clients who request this

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From a mechanistic standpoint, these observations are mediated by GLP-1R in monocytes/macrophages and glomerular endothelial cells (Kodera et al., 2011)

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We have reviewed previously the mechanistic explanations of how these multiple IO&NS pathways cause neuroaffective toxicity and, consequently, the onset of chronic fatigue syndrome and somatic and affective symptoms [28, 31, 81, 112,113,114]