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Mechanistically, the principal ketone body 3-hydroxybutyrate (3HB) in a KD prevented the ICB-mediated upregulation of PD-L1 on myeloid cells while simultaneously promoting the expansion of CXCR3 + T cells

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The ac-p65 protein, which is linked to the NF-B signaling pathway, and miR-323-3p were both expressed at higher levels in blood samples from patients with mild VEC or CHD atherosclerosis