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Single-atom nanozyme liposome-integrated microneedles for in situ drug delivery and anti-inflammatory therapy in Parkinsons disease

Pharmacokinetic/pharmacodynamic models should be applied to dynamically adjust platinum dosing, especially in elderly or renally impaired patients, to minimize excessive platinum accumulation while preserving anti-tumor efficacy

10.1038/s41374-022-00737-3 77 XuS.WuB.ZhongB.LinL.DingY.JinX.et al (2021)

Corinti D, Crestoni ME, Chiavarino B, Fornarini S, Scuderi D, Salpin J-Y (2020) Insights into cisplatin binding to uracil and thiouracils from IRMPD spectroscopy and tandem mass spectrometry