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Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies

Will it create disordered eating patterns that are going to cause other problems later in life? Though both doctors suggested that the results of this small trial could be beneficial when considering treatment options for children with severe obesity, especially when trying to head off comorbidities, its still telling that even experts who are not wholesale against GLP-1s or their use on children have such concerns

Similarly, in the CANVAS outcome study, discussed in detail below, LDL cholesterol and HDL cholesterol were also marginally increased in the canagliflozin treated group (LDL cholesterol 4-5 mg/dL and HDL cholesterol 2-3 mg/dL) (144)

Treatment is not guaranteed and is subject to provider discretion

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