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Exploration of structure-activity relationships at the two C-terminal residues of potent 11mer glucagon-like peptide-1 receptor agonist peptides via parallel synthesis

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The reaction was terminated by the addition of 400 L phase A (0.1% trifluoracetic acid) before being fractionated into 1 mL volume by reverse-phase high-performance liquid chromatography (RP-HPLC, Waters 600 SimiPrep system) on a C18 column