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It is synthesized from ATP and methionine by S -adenosylmethionine synthetase enzyme through the following reaction: ATP + L-methionine + H2O phosphate + diphosphate + S -adenosyl-L-methionine The sulfonium functional group present in S -adenosyl methionine is the center of its peculiar reactivity
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eBioMedicine 118 , 105836 (2025)
Multi-Pathway Skin & ECM Research The stack allows research designs to address nitric-oxide-pathway, actin-cytoskeleton, and copper-mediated ECM-remodeling mechanisms simultaneously, giving each compound a defined role in the same model system
10.1016/j.molmet.2018.12.008 245
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