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Further, a study focused on the angiogenic effect and counteraction of limb ischemia demonstrated that BPC 157 itself not only increased the VEGFR2 expression in vascular endothelial cells several hours after treatment but also immediately triggered the internalization of VEGFR2 within minutes [122]
Mezhnina V, Ebeigbe OP, Poe A, Kondratov RV
Acylation of the incretin peptide exendin-4 directly impacts glucagon-like peptide-1 receptor signaling and trafficking