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Other proposed mechanisms of mitochondrial damage that could result in statin-induced liver injury include inhibition of the respiratory chain (i.e., complexes I, II, and III) and the release of calcium (Fig

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Como consecuencia de los procesos mencionados, los mecanismos de muerte celular por necrosis se activan durante la fase de isquemia y los cambios caractersticos de la apoptosis ocurren principalmente tras reperfusin5, contribuyendo ambos tipos de muerte celular al tamao final del IM2

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