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Glucagon and GLP-1 receptor dual agonist survodutide for obesity: A randomised, double-blind, placebo-controlled, dose-finding phase 2 trial

Results showed a significant improvement in neuropathy symptoms, defined as a 1 grade reduction on NCI-CTC

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Across the controlled trials Volek's recovery work (PMID 11788381), the 2021 recovery trial (PMID 34684429), the centenarian fatigue trial (PMID 18065594), and the trials pooled in the 2016 weight meta-analysis (PMID 27335245) L-carnitine was generally well tolerated, with adverse events that were mild and did not drive meaningful discontinuation

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