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(A ) PLS-DA score plot as multivariate data analyses based on metabolomics data between three tamoxifen-treated groups (each group contains 9 samples) compared to the control group (n = 9)

However, because this distal site of action that cannot utilize tubuloglomerular feedback to ameliorate glomerular hyperfiltration [95, 96], DPP-4 inhibition does not appear to exert early benefits on renal function in type 2 diabetes

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