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Peer review Peer review information Nature Metabolism thanks Alice Adriaenssens, Nigel Irwin and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Portable oxygen systems allow the client to exercise, work, and travel

Cag 10: A long-acting synthetic analogue of human amylin, engineered with fatty acid acylation to extend its half-life and enable sustained amylin receptor activation over a significantly longer duration than native amylin allows

Unlike regular IGF-1, IGF-1 LR3 has an extended half-life, which prevents rapid degradation and allows it to remain active in the body longer (4)

Proc R Soc Lond B