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Risks and Side Effects While IGF-1 does have some important roles, on the other hand it has some negative effects when levels rise too high
The flux through pathways that require nonesterified CoA, such as the oxidation of glucose, may be reduced if all the CoA available in a given cell compartment is esterified
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Accordingly, LDL-derived cholesterol, internalised via endocytosis and stored in lipid droplets as cholesteryl esters, was shown to be essential for PCa cell growth [341]
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