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Mechanism with Numbers: How IGF-1 LR3 Works IGF-1R is a heterotetrameric receptor tyrosine kinase

Vivo growth inhibitory and radiosensitizing effects of Withaferin A on mouse Ehrlich Ascites carcinoma

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IGF-1 is useful precisely because it is slow-moving: unlike GH, whose serum level swings across a single pulse and is hard to capture with a spot measurement, IGF-1 integrates GH exposure over roughly a day, so a sustained rise in IGF-1 is strong evidence that GH output has genuinely increased rather than merely been re-timed

Webling KEB, Runesson J, Bartfai T, Langel (2012) Galanin receptors and ligands