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However, its metabolism places a significant burden on the livers detoxification and antioxidant systems , particularly through depletion of glutathione

doi: 10.1097/NEN.0000000000000037 154 GuneykayaDIvanovAHernandezDPHaageVWojtasBMeyerNet al

Consequently, cyclin T1-dependent Tat transcriptional activation is abolished, resulting in reduced gene expression and, ultimately, HIV production [170,171]

Meier P, Finch A, Evan G

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