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To address this concern, chimeric antigen receptor (CAR) T cells have shown promise in selectively and effectively removing senescent cells by identifying proteins broadly induced in these cells (108, 109)
Related Stories Popular diabetes drugs do not alter the risk of developing a blinding eye condition Blood ketone threshold may help predict weight loss success Weight loss drugs may reduce binge eating disorder symptoms Simultaneously, a growing body of evidence suggests that Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) are capable of crossing the blood-brain barrier (BBB) and interacting with the brain's reward and dopamine signaling regions, leading researchers to hypothesize that these originally weight-management-centric drugs could be used to address addictive behaviors, specifically regarding the suppression of ethanol-seeking triggers
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Wrbel H (2020) The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
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