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IGF-1 LR3 at research concentrations (95% HPLC, ESI-MS confirmed molecular weight ~9.1 kDa) should be verified for correct LR3 sequence (Arg extension, Glu3Arg substitution) versus native IGF-1 contamination

For example, the inhibition of cell proliferation by curcumin has been associated with the Nrf2-dependent downregulation of DNA repair-specific flap endonuclease 1 (Fen1) in breast cancer cells in culture (46)

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