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doi: 10.1210/me.2005-0483

Toniiqs berberine is sourced from the mineral-rich foothills of the Himalayas, an environment believed to support higher levels of active compounds and nutrients

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The predicted binding pose revealed that the compound establishes stabilizing interactions with a set of hydrophobic and aromatic residues lining the transmembrane binding cavity (Figure 4), including A200, L201, M204, L217, Y220, V229, and W297