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Nishinaka-Arai, Y

This pharmacokinetic profile is important when planning discontinuation, as you'll need to account for this extended washout period when considering alternative diabetes management strategies or if you're experiencing adverse effects

By 48 weeks, significant average weight loss was seen at all maintenance doses: With longer treatment lasting up to 68 weeks, weight loss continued, particularly at higher doses: 12mg: average weight loss of up to 28.7% of body weight This longer-term data shows that weight loss with retatrutide can continue beyond one year, rather than plateauing early, especially at higher maintenance doses

Ethics declarations Competing interests G.R.S

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