10.1046/j.1365-2125.2003.01717.x 134 SeibelB
Targeting transporters: Promoting bloodbrain barrier repair in response to oxidative stress injury
[DOI] [PubMed] [Google Scholar] 29.Vecchiet L, Di Lisa F, Pieralisi G, Ripari P, Menabo R, Giamberardino MA, Siliprandi N
Our results show that when sensitive cells were treated with each drug, an oxidative stress took place as assessed by the decrease of the GSH/GSSG ratio demonstrating a general unspecific toxic effect of both antifungal drugs on redox balance
260,261 Owing to its rate-limiting enzymatic activity in NAD + salvage pathway, the elevated expression of NAMPT in the innate immune cells, including macrophages and dendritic cells, further proposed a link between intracellular NAD + levels and inflammation