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Safety and efficacy of tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan (SURPASS J-combo): a multicentre, randomised, open-label, parallel-group, phase 3 trial

NAC has been shown to be efficacious in reducing the symptom burden [70], especially negative [71] and cognitive symptoms [72], and has the potential to alleviate treatment resistance in schizophrenia [73]

34 In a similarly sized double-blind, placebo-controlled study of intravenous ketamine (0.2 mg/kg) for treatment of migraine in the emergency department setting, however, ketamine was not superior to placebo for acute pain relief and caused adverse effects of generalized discomfort at 30 minutes and fatigue at 60 minutes, although no serious adverse events occurred

Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis

doi: 10.1007/s10059-013-0228-1 141 Join-LambertO.LecuyerH.MillerF.LelievreL.JametA.FurioL.et al