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The 12-month EFS rate was 83.7% (95% CI, 73.8%94.8%) in the neoadjuvant group and 57.2% (95% CI, 45.1%72.7%) in the adjuvant-alone group.[21][Level of evidence B1] The benefit of neoadjuvant therapy was seen across all subgroups of patients, including those with BRAF pathogenic variants

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Furthermore, it is to determine whether the risk may differ by GLP-1RA type, trial duration, control type, and indication

Dosage Recommendations: Typically, 600mg is administered 13 times per week, depending on individual needs and professional advice