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Patients must be clearly informed of the risks associated with nonFDA-approved products, including potential contamination, inaccurate dosing, variable bioactivity, and the presence of impurities that may provoke adverse or unpredictable effects

Typically, injections may be given weekly or monthly initially, then less frequently once levels stabilize

However, according to results of a web-based survey between August 2019 and April 2020 within 2,385 AAS users (Bonnecaze et al., 2020), the main PED used during AAS cycle were anastrozole (48%), tamoxifen (31%), exemestane (30%), and hCG (29%), whereas tamoxifen (40%), clomiphene (32%), hCG (26%), anastrozole (16%), exemestane (9%), letrozole (3%), and cabergoline/bromocriptine (1.6%) were used as PCT