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For instance, prior articles have focused on immune-boosting encapsulated foods in the context of COVID-19 or on advances in liposome formulation techniques and safety aspects ( 2 Historical trajectory of nanoencapsulation: key developments and breakthroughs 2.1 Conceptual emergence and theoretical foundations The intellectual origin of nanoencapsulation can be traced back to the mid-20th century

10.1038/s41467-020-20154-8 Nat

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This is due to a lack of bioavailability , which refers to the proportion of a substance that enters the circulation when introduced into the body and is so able to have an active effect

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