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10.1016/S0140-6736(17)32284-5 26
Antioxidant status was most significantly impaired in untreated patients, confirming that the level of antioxidants in patients with schizophrenia is tightly related to the suppression of pathological manifestations of the disease (Goh et al
76 LiH.GuoW.LiS.SunB.LiN.XieD.et al (2024)
For instance, neurons and astrocytes treated with rotenone (25 to 50 nM) showed an altered expression of g-tubulin and a disorganization of the centrosome with aggregates of -synuclein [70]
The insulin/IGF-1 signaling pathway seems to be an evolutionarily well-conserved mechanism involved in the regulation of longevity in species ranging from metazoans to mammals [1, 2]
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