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Beyond its monotherapy potential, HM17321 has also demonstrated additive efficacy when used in combination with incretin-based agents, further expanding its versatility as a next-generation obesity solution

Silent information regulator 1 (SIRT1)/OpticAtrophyType1 (Opa1) signaling pathway In a palmitic acid (PA) induced hepatocyte IR cell model, the deficiency of Opa1 often leaded to an imbalance in mitochondrial fusion/fission, impairing the insulin signaling pathway

Data Last Updated 06/08/2026

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